Video: Natural Cancer Cure? Man Cures Himself Then Thrown In Jail ( YOU CAN'T CALL IT A CURE )
By Marion Algier - Ask Marion - Cross-Posted at THITW
1600+ Americans die every day of Cancer. At the turn of the 20th Century 1 in 200 Americans developed Cancer… today (2015) 1 out of 3 Americans will have Cancer during their lifetime.
I have been blessed to have been amazingly healthy all my life. I was days short of turning 62-years-old, had never been in a hospital for anything related to myself and had probably only ever been to see a doctor 20 times in my entire life when I was diagnosed with Uterine Cancer. And although my father, who had been just as healthy all his life as I’ve been until he was stricken with Colon Cancer at age 62… and died at age 63, it never really occurred to me that I would ever have Cancer. After our dad died, the doctor told us that chances were very high that one of us 3 kids would develop Colon Cancer and it was something we should watch out for and be tested for. My brother died at age 21 so my sister and I jokingly said more than once, “Well, since Rick is no longer with us, let us hope that it would have been him that was destined to come down with the Cancer.”
After closing our business as a result of the tough economy, my husband and I had moved in with his 80 plus year old parents to get back on our feet and to help take care of them. His father was in late stage Alzheimer’s and his then 82-year-old mother was overwhelmed, suffering from Rheumatoid Arthritis, had failing hearing, and as I call them, suffered from senior related conditions and ailments. And after inheriting a substantial amount of money from their parents and a couple aunts, they made a number of unwise purchases and unguaranteed loans and then got scammed by a Jamaican ring that prays on the elderly and uninformed. Before anyone realized it, they not only bankrupted themselves but scavenged their grandchildren’s college funds as well as opened a reverse mortgage that they overdrew once the housing bubble burst, so their house was essentially gone too! I have been an unpaid caregiver for over two years in a stressful environment, and still am, and my architect husband an unpaid handyman and part-time caregiver while applying for and trying countless part-time and commission jobs that went nowhere and sometimes cost us money. Then he got a lead and went to truck driving school which gave us medical coverage after 3-months.
I had known for several months that something was wrong; I was sick. But even though insurance companies can no longer deny you coverage due to pre-existing conditions, they can charge you high premiums because of them. So I waited to go to the doctor until I knew we had coverage and could go without having costly pre-existing conditions. As it was we had had 12k family co-pay.
On October 1st, a week before my 62nd birthday, I was diagnosed with stage 3 inoperable (because of the location of the tumor and the outlying ribbons from the tumor) Uterine Cancer. And from the looks in their eyes and little innuendoes, I could see that nobody other than my husband and our new GP thought I was going beat the disease.
At some point you start feeling alone unless you make contact with other Cancer patients or Cancer survivors because nobody understands what the disease or the treatments are like unless they have gone through it. And even with a support group of family, friends and Cancer survivors, get used to feeling both lonely and alone. For me it was probably worse because my husband got a job where he was gone weeks, sometimes nearly two months without coming home for usually 4 or 5 days. He gave up being home for any of the major holidays including Thanksgiving, Christmas, New Years and even his birthday in order to be there for my chemo treatments. At first that seemed like a fair trade but after the first couple of treatments, the company stopped making the effort to get him home.
Video: How the American Cancer Society spins survival data
Natural Society: Recently, the results of a study claiming that most Cancers are caused by “bad luck” have been floating around in the mainstream media. This sounds like we should all just give up and accept our likely fates of cancer, chemo, and death, right? However, there is a mountain of evidence showing that cancer is in fact preventable, partly because tumor development is a bit too complex to be bad luck.
Most Cancers are “Beyond Your Control’ Due to Mutations
For many years, the “Mutational Theory” has been the dominant explanation for cancer’s origin. The story goes like this: accumulated mutation in all the right places lead to the affected cell going “crazy,” and instead of destroying itself after this damage, it grows out of control until vital processes are obstructed. Then, the heroic oncologists attempt to wage war against this monster with one or more of the standard trio of chemo, radiation, and surgery…with often disappointing results.
One 2004 study of thousands of patients found that chemo is less than 10% effective at saving lives, contributing only 2.1-2.3% of the 5 year survival rate. This was deemed to be the upper limit of effectiveness.
More recently, it was reported that out of 54 cancer drugs released since 2004, three quarters of them did not extend life. Unfortunately, chemotherapy is often forced on young people who refuse it, such as in a recent case involving a Connecticut teenager, meaning it could be considered as a tool or form of oppression. Therefore, it’s wonderful that in actuality, cancer is not the result of chance or luck, as well as being unlikely; and the theories behind the development of cancer drugs are most likely incorrect.
Read: 4 Cancer-Fighting Foods
What is the nature of a tumor? Tumors express organized behaviors including building their own blood supply; silencing some genes and activating others; secreting corrosive enzymes; altering their metabolism for low oxygen and high sugar, acidic environments; as well as removing surface proteins to escape the immune system.
A new theory, however, states that cancer is actually a highly efficient, pre-programmed stress response. According to the author’s research, cancer is an evolutionary throwback from a genetic “tool kit” over a billion years old that is normally buried dormant deep within the genome, called Metazoa 1.0.
Cells with the genetics of Metazoa 1.0 would have favored traits that enable them to survive a much harsher environment with features such as extremely low oxygen. The trait of incessant proliferation was the default state of these primitive cells, when simply not dying was the first priority of individual cells.
There was no tissue specialization that organisms could use to protect themselves, so genes providing extreme resilience against assault and creating a highly “selfish” form of behavior was necessary. While the mutation theory is partially true, genetic damage is responsible for unmasking a primitive set of genes instead of being solely responsible for tumor development.
Additionally, an analysis of gene expression patterns has indicated that when the level of oxygen decreases, the rate of glycolysis (a pathway of cellular energy production that does not require oxygen) increases, and this leads to a vicious cycle of accelerated tumor growth and further reductions in oxygen. The production of new blood vessels to ensure a supply of glucose only gives temporary breaks from this cycle.
The current understanding of this is that glycolysis is not only faster at generating energy when glucose is abundant, but also that glycolysis provides some of the raw materials needed for rapid cell proliferation. A key driver of this process was found to be reduced energy efficiency caused by factors such as hypoxia, which triggers a dramatically increased glucose uptake and a switch to glycolysis. This can also allow the tumor to select “positive” mutations such as those that upregulate Cancer promoting genes and silence or delete suppressor genes, no random mutations required.
Read: Little Known Chinese Herb and Iron Kill Crazy Amount of Cancer Cells
When seven cancer types were tested, expression of genes turned on only during replication increased as oxygen levels dropped. Therefore, cancer is not a time bomb or a result of bad luck, but instead caused by an ancient survival response to a toxic environment, unnatural diet and compromised immunity.
So what can we do to prevent Cancer, besides reducing excessive dietary sugar?
6 Tips for Preventing Cancer
- 1. Regular coffee consumption can reduce the incidence of some Cancers, but watch the acidity levels of your body. Book: The Acid-Alkaline Food Guide - Second Edition: A Quick Reference to Foods & Their Efffect on pH Levels
- 2. A review from 2012 found that sun exposure may also lower the risk of Cancers such as breast, colon, and pancreatic cancer, because of vitamin D synthesis (getting burnt will remove the benefits), and prolonged or excessive sun exposure can cause skin Cancer.
- 3. A study of almost 24,000 participants showed that those taking antioxidant supplements from the beginning had a 48% reduced risk of cancer. This can mean that increased antioxidant intake from food or supplements can reduce cancer incidence, as many other studies show that certain foods high in antioxidants and other nutrients have the ability to protect against Cancer.
- 4. Quit smoking. Cigarette smoking, which depletes antioxidants, is responsible for a third of all Cancer deaths in many countries.
- 5. Reduce or eliminate, if possible, the use of pharmaceutical drugs. Statins, the contraceptive pill and many others are associated with a higher risk of Cancer.
- 6. Interestingly, cannabis smoking is associated with a 45% reduced risk of bladder cancer and a 47-62% reduced rate of head and neck cancer, regardless of whether or not they had been infected with HPV. And using hemp oils increases the survival success rate of treatments like chemo and radiation by 25%.
Despite what the mainstream media tries to make people believe, Cancer is indeed preventable and not caused by “bad luck.” This is good news, because not only are Cancer and its conventional treatments very debilitating and distressing, but they hinder control over one’s life – which is a natural psychological need, as described by self-determination theory.
So what can you do if you are diagnosed with Cancer?
After you are diagnosed:
- Take control of your destiny.
- Do your homework.
- Question the treatments the doctors suggest.
- Look for alternatives.
- Add natural cures and aids to the traditional western medical treatments even if you decide to go that route.
- Have a back-up plan.
- Keep up your attitude.
- Cut your stress.
- Pray.
- Be positive.
- Stay out of the doldrums and away from pity parties as much as possible.
- Surround yourself with things that make you happy… pets, photos, music, etc.
- Limit your exposure and dealings (as much as you can) to negative people and situations.
- Make plans for the future.
Because my husband was gone regularly through my entire treatment time, and my father-in-law was in the late stages of Alzheimer’s at home and died during the first four months of my treatment, I had no choice but to rely on myself for my attitude, research and to be prepared for any and all side affects from the treatments.
I think I did a pretty good job through the chemo process and with each check-up my oncologist was shocked at my progress.
- I never questioned that I would beat my Cancer
- I prayed and talked to God daily, throughout the day, in a positive manner; thanking Him for curing me and making me completely Cancer free.
- I moved 600 photos that made me happy onto my phone and kept adding to it.
- Our four furkids, a Chihuahua and three Chiweenies, never left my side.
- I visualized my tumor and the outlying ribbons shrinking and being gone daily.
- I only ever allowed myself one 10-minute pity party.
- I drank a teaspoon of baking soda in water every morning, sometimes twice a day.
- I ingested 4 squirts of food grade hydrogen peroxide daily.
- I used the oxygen machine provided by hospice for my father-in-law every evening for 5 to 10 minutes and inhaled the pure oxygen.
- I got a vitamin B Complex shot weekly.
- I took vitamins, iron, probiotics, krill oil and phytoplankton daily.
- I researched every option from hemp oils and immunotherapy to alternative health centers like Sanoviv.
- I added things like raw sauerkraut fermented with whey, extra protein and more organic veggies, fruit and meat to my diet.
Sources:
Experimental treatment uses immune system to fight Cancer – Immunotherpy coming to US in 2015
Breakthrough! Have The Israelis Developed A Cure For Cancer?
A Natural Herb That Fights Cancer, or Chemotherapy for Your Sick Pet… Which Would You Choose?
This New Drug Appears to Cause Cancer Cells to Self-Destruct
How to Stave the Cancer Out of Your Body
Beat Prostate Cancer Naturally
America’s Drug Story and the Rockefeller Empire
Ella institute for melanoma - Dr. Gal Markel
Books
Experimental treatment uses immune system to fight cancer - Immunotherpy finally coming to US. Clinical trials coming in 2015 through Avaxis for metastatic Cancers.
Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Source: National Institute of Allergy and Infectious Diseases (NIAID).
The immune system’s natural capacity to detect and destroy abnormal cells may prevent the development of many cancers. However, some cancers are able to avoid detection and destruction by the immune system. They may produce signals that reduce the immune system’s ability to detect and kill tumor cells, or they may have changes that make it harder for the immune system to recognize and target them.
Immunotherapies are treatments that restore or enhance the immune system’s ability to fight cancer. In just the past few years, the rapidly advancing field of cancer immunology has produced several new methods of treating cancer that increase the strength of immune responses against tumors. These therapies either stimulate the activities of specific components of the immune system or counteract signals produced by cancer cells that suppress immune responses.
The journal Science designated "immunotherapy of cancer" as its Breakthrough of the Year in 2013 to recognize the progress made in this area. These advances are the result of long-term basic scientific research on the immune system.
Additional research is underway to:
One immunotherapy approach is to block the activity of certain proteins that limit the strength of immune responses. These proteins normally keep immune responses in check to prevent overly strong responses that might damage normal cells as well as abnormal cells. In cancer cells, these "checkpoint" proteins may be abnormal and may help tumors to evade the immune response.
Blocking one of these checkpoint proteins could lift the brakes on the immune system, enabling it to destroy cancer cells. The first immune checkpoint modulator to gain Food and Drug Administration (FDA) approval is called ipilimumab (Yervoy). This immunotherapy drug, a monoclonal antibody, blocks the activity of a checkpoint protein called CTLA4 and has been approved to treat advanced melanoma.
An experimental form of immunotherapy is adoptive cell transfer (ACT). In one form of ACT, cytotoxic T cells that have invaded a patient’s tumor, called tumor-infiltrating lymphocytes (TILs), are harvested. The cells with the greatest antitumor activity are selected, and large populations of these cells are grown in the laboratory and activated with cytokines. The cells are then infused back into the patient.
The idea is that TILs already have the ability to target tumor cells but may not be present in sufficient amounts to exert an antitumor effect. If the activity of the TILs is being suppressed by the tumor cells, it may be possible to overcome that suppression by exposing the tumor to massive amounts of activated TILs.
In another form of ACT, often referred to as CAR therapy, a patient’s T cells are collected from their blood and genetically modified to express hybrid proteins called chimeric antigen receptors (CARs) before they are expanded and infused into the patient. The CAR allows the cells to attach to specific proteins on the surface of cancer cells, which activates the T cells to attack those cells.
The use of cancer treatment (or therapeutic) vaccines is another approach to immunotherapy. These vaccines are usually made from a patient’s own tumor cells or from substances taken from tumor cells. They are designed to treat cancers that have already developed by strengthening the body’s natural defenses against the cancer. Treatment vaccines may act in any of several ways:
Developing effective cancer treatment vaccines requires a detailed understanding of how immune system cells and cancer cells interact. To be effective, cancer treatment vaccines must stimulate specific immune responses against the correct target. The immune responses must also be powerful enough to overcome the barriers that cancer cells use to protect themselves from attack by B cells and killer T cells.
Recent advances in understanding how cancer cells escape recognition and attack by the immune system are now giving researchers the knowledge required to design cancer treatment vaccines that can accomplish both goals.
In 2010, the FDA approved the first cancer treatment vaccine, sipuleucel-T (Provenge), for use in some men with metastatic prostate cancer.
Yet another type of immunotherapy uses immune-modifying agents, such as cytokines, antibodies, and growth factors, to enhance the body’s immune response against cancer. Cytokines are signaling proteins that are produced by white blood cells, and they help regulate immune responses. Two types of cytokines are used to treat patients with cancer: interferons and interleukins.
Dr. Steven A. Rosenberg, Chief of Surgery at the National Cancer Institute, developed the first effective immunotherapies and gene therapies for patients with advanced cancer.
Immune-modifying agents may work through different mechanisms. A type of interferon, for example, enhances a patient’s immune response to cancer cells by activating certain white blood cells, such as natural killer cells and dendritic cells. Recent advances in understanding how cytokines stimulate immune cells could enable the development of more effective immunotherapies and combinations of these agents.
Research at NCI
Immunotherapy research at NCI is done across the institute and spans the continuum from basic science discoveries to clinical research applications.
The Center of Excellence in Immunology (CEI) brings together researchers from across NCI and other NIH institutes to foster the discovery, development, and delivery of immunotherapy approaches to prevent and treat cancer and cancer-associated viral diseases.
See More at Fox Heath News: http://video.foxnews.com/v/3963227537001/experimental-treatment-uses-immune-system-to-fight-cancer/?playlist_id=930909749001#sp=show-clips
Also See:
Related Resources
(NaturalNews) Ever since the mid 70s, medical scientists have been well aware of the beneficial effects of cannabinoid compounds over cancerous cells. Thanks to modern science, over a dozen studies conducted during recent years have been able to partially reveal just how it works. Yet cannabis is still not endorsed by pharmaceutical companies as a cancer cure, and since it is not promoted through mainstream channels, very few people are aware of its benefits. Consequently, it is not sought after as an alternative to disfiguring chemotherapy and other harmful drugs.
Laboratory tests conducted in 2008 by a team of scientists formed as a joint research effort between Spain, France and Italy, and published in The Journal Of Clinical Investigation, showed that the active ingredient in marijuana, known as tetrahydrocannabinol or THC, can function as a cure for brain cancer by inducing human glioma cell death through stimulation of autophagy.
The study concluded that via the same biochemical process THC could terminate multiple types of cancers, affecting various cells in the body. Other studies have shown that cannabinoids may work by various mechanisms, including inhibiting cell growth, inducing cell death, and inhibiting tumor metastasis.
What is amazing is that while cannabinoids effectively target and kill cancerous cells, they do not affect healthy, normal cells and may actually protect them against cellular death. Moreover, cannabinoids are also researched for their pain-modulation and anti-inflammatory abilities as they bind to special receptors in the brain, much like opioid derivatives that are commonly prescribed today.
Further evidence to support the effects of cannabis extract on malignant cells comes from the real life experience of individuals who have successfully overcome cancer by using cannabis oil. Examples include a patient, who managed to completely cure his skin cancer by simply applying cannabis oil onto the affected areas of the skin, as well as another, who recovered from a severe head injury with the aid of hemp oil.
One of the cannabinoids that has displayed amazing medical properties is cannabidiol, or CBD - a non-psychoactive compound that is regarded by some as the medical discovery of the 21st century, and with good reason. Research indicates that CBD can relieve convulsions, reduce inflammation, lower anxiety and suppress nausea, while also inhibiting cancer development. In addition, CBD has exhibited neuroprotective properties, relieving symptoms of dystonia and proving just as effective as regular antipsychotics in the treatment of schizophrenia.
What stands out is that from the vast amount of research and data available, as well as the personal experiences of cancer survivors, is that no chemotherapy currently being used medically can match the non-toxic anti-carcinogenic and anti-tumorigenic effects of these natural plant compounds.
Sources for this article include:
http://safeaccess.ca/research/cancer.htm
http://www.jci.org/articles/view/37948
http://dotsub.com/media/fc4e051a-1709-4e63-8...
http://en.wikipedia.org/wiki/Cannabidiol
About the author:
Raw Michelle is a natural health blogger and researcher, sharing her passions with others, using the Internet as her medium. She discusses topics in a straight forward way in hopes to help people from all walks of life achieve optimal health and well-being. She has authored and published hundreds of articles on topics such as the raw food diet and green living in general.
Aging…No longer inevitable, for mice (Image: Design Pics Inc/Rex)
New Scientist: Imagine if we could turn back time. A team that has identified a new way in which cells age has also reversed the process in old mice whose bodies appear younger in several ways. The discovery has implications for understanding age-related diseases including cancers, neurodegenerative disorders and diabetes.
One way all mammalian cells produce energy is via aerobic respiration, in which large molecules are broken down into smaller ones, releasing energy in the process. This mainly occurs in the mitochondria – the "powerhouses" of cells. Mitochondria carry their own genomes, but some of the cellular components needed for respiration are produced partly by the nucleus, so the two must coordinate their activities.
As we age, mitochondrial function declines, which can lead to conditions such as Alzheimer's disease and diabetes. To investigate why this decline occurs, Ana Gomes at Harvard Medical School and her colleagues compared the levels of messenger RNA (mRNA) – molecules that convey genetic information around a cell – for the cellular components needed for respiration in the skeletal muscle of 6 and 22-month-old mice.
They found that the level of the mRNA in the nucleus did not change much between the young and old mice, whereas those from the mitochondria appeared to decline with age.
Similar changes were seen in mice that lacked a protein called SIRT1 – high levels of which are associated with calorie restriction and an increased lifespan. These mice also had higher levels of a protein produced by the nucleus called hypoxia inducible factor (HIF-1α).
What was going on? It appears that communication between the nucleus and the mitochondria depends on a cascade of events involving HIF-1α and SIRT1. As long as SIRT1 levels remain high and the two genomes communicate well, ageing is kept at bay. But another molecule called NAD+ keeps SIRT1 on the job; crucially, the amount of NAD+ present in the cell declines with age, though no one knows why, leading to a breakdown in communication.
The team wondered if this aspect of ageing could be reversed by increasing the amount of SIRT1 in the cells. To find out if that was possible, they injected 22-month-old mice twice daily for a week with nicotinamide mono nucleotide (NMN) – a molecule known to increase levels of NAD.
At the end of the week, markers of muscular atrophy and inflammation had dropped and the mice had even developed a different muscle type more common in younger mice. Together, these features were characteristic of 6-month-old mice.
"We found that modulating this pathway can improve mitochondrial function and age-associated pathologies in old mice, and therefore it gives a new pathway to target that can reverse some aspects of ageing," says Gomes.
"This paper clearly demonstrates that NAD+ production is a sort of 'Achilles' heel', [a lack of which] significantly contributes to ageing, and also that this problem can be ameliorated by boosting NAD+ production with key intermediates, such as NMN," says Shin-Ichiro Imai, at Washington University School of Medicine in St Louis, Missouri.
Journal reference: Cell, DOI: 10.1016/j.cell.2013.11.037
Video: Dr. Becker Interviews Dr. Scanlan
By Dr. Becker - Cross-Posted at Just One More Pet
In this week’s third and final video, I’m chatting with another very special guest, Dr. Nancy Scanlan. Dr. Scanlan is the Executive Director of the American Holistic Veterinary Medical Foundation (AVHMF) and also the American Holistic Veterinary Medical Association (AHVMA).
Dr. Scanlan has been a small animal practitioner for most of her veterinary career. She also spent 10 years teaching veterinary technicians. Dr. Scanlan is an authority on the use of nutraceuticals in veterinary medicine, and was certified as an acupuncturist in 1988. She gradually increased her use of holistic therapies in her practice and ultimately spent 16 years as the sole holistic veterinarian in a seven-person practice in Southern California. Since then, she’s been very involved in a variety of wonderful endeavors for the AVHMA and the Foundation.
Dr. Scanlan currently lives in the woods of northern California. Her home is off the grid, meaning that among other things, she uses solar panels as her source of electricity. I think that’s very cool!
The theme of this year’s AHVM Foundation Be One in a Million fundraising campaign is “Advancing Research and Education in Holistic Veterinary Medicine.” I asked Dr. Scanlan to talk about why cancer research for companion animals is such a vitally important area for the AHVMF to be involved in.
Dr. Scanlan explained that studies in holistic medicine get very little funding. If she has an herb that is beneficial in treating cancer, chances are it will be ignored by the big drug companies, which are the major source of funding for most human and animal cancer research. Drug companies only fund research that results in new drugs they can sell, so natural healing substances like herbs are of no interest to them. And this is truly a shame, because many holistic therapies used for cancer have fewer side effects than conventional chemotherapy and radiation treatments. They are less toxic to the patient and the environment, and are generally better for the patient’s overall health.
So raising independent funding for holistic and integrative cancer therapies is a very important focus of the AHVM Foundation. The goal is to provide scientific proof to veterinarians and pet owners of the benefits of alternative therapies. Currently there is no “proof” of the type the medical community relies on. It’s really not enough to say “The Indians used it all the time,” or “In China they’ve used this for thousands of years.” MDs and DVMs want and need this research.
Another reason we need independent studies of holistic remedies is to determine how natural substances can and should be used. For example, what parts of a plant are beneficial to treat different diseases and symptoms … what strengths or dosages are most effective … what type of growth environment is best … should we source only the wild-crafted plants, and so on.
As Dr. Scanlan points out, this type of research would be helpful not just in advancing the field of holistic veterinary medicine, but also for current and future holistic practitioners who want to understand the most effective ways to use natural healing remedies. And in general, good standardized research in holistic treatments is needed.
Next I asked Dr. Scanlan to give her perspective on why there is a need for a foundation for holistic veterinary medicine. She explained that the AHVM Foundation is the only organization in the U.S. specifically dedicated to research into holistic methods of treating animals. No other group currently in existence raises funds for research into holistic or alternative or integrative veterinary therapies exclusively.
As Dr. Scanlan points out, there are plenty of organizations out there dedicated to raising money for conventional medicine research (human and animal). But if you as a pet owner, pet caretaker, pet guardian or animal lover believe holistic and integrative veterinary medicine has value, then the organization you want to give your hard-earned money to is the AHVM Foundation.
I asked Dr. Scanlan what projects are on the horizon that the AHVMF is involved with. She responded that one of the Foundation’s biggest supporters is Dr. Greg Ogilvie, a DVM in southern California (you might remember his name from my recent interview with author Ted Kerasote).
Dr. Ogilvie developed the foundational research on the anti-cancer effects of omega-3 fatty acids, especially fish oil, on dogs. He has a long list of projects he would love to do if he had the funding.
I’d like to thank Dr. Nancy Scanlan, Executive Director of the AHVM Foundation, for making time in her busy schedule to chat with me today. I look forward to working with Dr. Scanlan and all the members of the Foundation to raise awareness of their Be One in a Million fundraising efforts.
I’m tremendously excited to announce that now through March 17, 2013, all donations will be automatically tripled. That’s right! For every $1 donated, Mercola Healthy Pets will donate an additional $2. So please, take a moment right now to Be One in a Million and make a donation to the AHVM Foundation.
Related:
Using Alternative Therapies to Fight Cancer How to Check Your Pet for Signs of Cancer
Pukka’s Promise: The Quest for Longer-Lived Dogs
Merle’s Door: Lessons from a Freethinking Dog
StemPets and StemEquine – Stem Cell Enhancers for Pets
If I Should Die Before My Dog…
Alternative Dog Arthritis Treatment Series Part 1 – An Introduction
Do Vaccinations Affect the Health of our Pets?
Natural Pet Remedies For Everyday Problems
Animal Chiropractic Success Stories
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The Cancer Answer Video: DCA Cancer Cure Discovered
By Dr. Mercola
According to the American Cancer Society, the odds you'll develop cancer in your lifetime are one in two, if you're a man, and one in three, if you're a woman.1 But an experimental cancer drug shown to shrink tumors by correcting metabolic oddities in cancer cells shows promise in the fight against this deadly disease. The synthetic drug DCA (dichloroacetate) DOES indeed kill cancer cells, both in the lab and in human beings. However, whether it can reverse tumor growth without harming you in other ways remains to be seen.
The first clinical trial, although small, involving patients with brain cancer (glioblastoma) was encouraging, and the results were published in Science of Translational Medicine in 20102 . However, there is still a great deal more work to be done before DCA can be pronounced a safe and effective cancer treatment.
An interesting aspect of DCA is that it's an inexpensive, non-patentable molecule, which makes it of minimal value to pharmaceutical companies that profit by patenting expensive new drugs. Therefore, clinical trials are slow to get going due to lack of funding by Big Pharma. Researchers must await sufficient money to trickle in from government sources and public donations before moving forward.
In the paragraphs below, my aim is to give you information from both sides of the story—the potential benefits as well as the possible risks.
The impetus behind most of the DCA research has been cardiologist Evangelos Michelakis of the University of Alberta in Edmonton, Canada. In 2007, Michelakis and his colleagues sparked a firestorm of interest when they announced rats fed DCA showed rapid tumor regression without any apparent side effects. Michelakis has been the first to say these results are preliminary and cautions cancer patients to refrain from running out and buying the drug, prior to clinical trials.
Yet, many desperate cancer patients with few remaining options are doing just that, and side effects ARE being reported.
There are currently three clinical trials involving use of DCA to treat cancer that are currently recruiting participants3. Some of these studies plan to combine DCA with other chemotherapy drugs and radiation, all known to have damaging effects in your body. However, if you have cancer and are tempted to participate, there are some things you should know in order to make an informed decision about the risk versus the benefits of this experimental treatment.
In order to understand how DCA kills cancer cells, it is necessary to understand a bit about how the cellular metabolism of cancer cells differs from that of your normal, healthy cells. Cancer cells have very different metabolic processes than normal cells, in terms of how they derive their energy.4 It's a rather complicated distinction, so please bear with me as I try to explain it in the simplest terms possible.
There are two major pathways your cells use to covert sugar into energy: glucose oxidation and glycolysis:
- Glucose oxidationis the primary energy metabolism in normal cells and takes place in your mitochondria, which are the little "power plants" inside your cell; it requires the presence of oxygen, as its name suggests. This is why you breathe and your heart beats to circulate oxygen throughout your body. Glucose oxidation is sometimes referred to as cellular respiration.
- Glycolysis takes place in your cell's cytoplasm. It can occur without the presence of oxygen. Glycolysis is less efficient for normal cells, but it is a cancer cell's preferred means of energy metabolism, and it depends on the availability of sugar.
So, when your cells are oxygen-starved they have a backup plan. They can extract energy from sugar without the presence of oxygen, by glycolysis.
Pyruvate is required for glucose oxidation. There is an enzyme (pyruvate dehydrogenase kinase, or PDK) that acts as gatekeeper to regulate the flow of pyruvate into the mitochondria. If PDK is active, it suppresses the transport of pyruvate into the mitochondria, and your cell is forced to rely on glycolysis, even if oxygen is available. If PDK is inactive, pyruvate is shuttled into the mitochondria, even if oxygen is low.
Unlike normal cells, cancer cells are masterful at deriving energy from glycolysis—they have very active PDK. The way to make a cancer cell unhappy is by suppressing PDK, forcing the cell to use glucose oxidation, instead of glycolysis. This is called the Warburg theory of cancer, or the Warburg hypothesis5.
This is where DCA comes in.
DCA suppresses PDK (the mitochondrial gatekeeper), and this fires up the cell's mitochondria. Not only does this force the cancer cell to abandon its preferred metabolic process, but it flips the cell's "suicide switch" as well. This happens because mitochondria are the primary regulators of apoptosis, or cellular suicide—they are loaded with sensors that react to abnormalities by pushing the cell's self-destruct button.
When a cancer cell's mitochondria realize it's a cancer cell, it spontaneously kills itself. This is the reason chemotherapy and radiation result in such terrible side effects—your healthy cells actually die much more easily because of this self-destruct button.
The reason cancer is so fast growing is that the mitochondria have been deactivated, so the cells evade apoptosis, as well as being able to grow in the absence of oxygen (glycolysis)6. DCA reverses this.In effect, DCA directly causes cancer cell apoptosis and works synergistically other cancer therapies, such as radiation, gene therapy, and viral therapy. A number of scientific studies have been performed to date, and most are encouraging.
Most of the studies thus far have been done on cell cultures in the lab (in vitro), as opposed to on cancer patients themselves (in vivo). Yet the results are impressively consistent across the board, suggesting DCA is effective against a wide variety of cancer types. The DCA Site7 has a good list of all clinical studies through 2011.
The study that sparked the DCA excitement appeared in Cancer Cell in January 20078 According to an article in the Edmonton Journal9 in the 2007 rat study, DCA killed lung, breast, and brain cancer cells but left healthy cells alone. The rats' tumors decreased by up to 70 percent in three weeks of DCA treatment, without negative side effects.
This announcement led to a cyclone of excitement from cancer patients everywhere who scrambled to get their hands on the new "cancer cure," in spite of warnings from Michelakis himself (and others) against prematurely self-medicating with the compound.
Several more studies soon followed, including the first clinical trial2 involving brain cancer patients. In that trial, the research team selected five glioblastoma patients with a particularly aggressive form of brain cancer. They treated them with oral DCA for 15 months.
Tumor tissue was compared before and after DCA treatment in three of the five patients. In all three, there were signs that the tumor growth had slowed, and more cancer cells were undergoing programmed cell death after the treatment with DCA. Unfortunately, one of the five patients died. Another had "debulking" surgery before completing the full course of DCA treatment.Below are some of the other DCA cancer studies, all within the past five years. (Note that none of these involved human subjects.)
- Endometrial Cancer: DCA causes apoptosis in endometrial cancer cells.10
- Prostate Cancer: DCA produces significant cytotoxic effects in prostate cancer cells11
- Breast Cancer: DCA has anti-proliferative properties against breast cancer cells and caused apoptosis of those cells12
- Colorectal Cancer: DCA reduced colon cancer tumors by 20 to 40 percent13
- Cervical Cancer: Researchers concluded DCA is a quick and effective cure for advanced cervical carcinoma14
For comprehensive information about DCA's method of action, history, and related scientific research, refers to The DCA Site7, and to this 2011 article in the International Journal of Cancer15. It should be noted that caffeine may radically increases the effects of DCA16. In fact, this effect is so pronounced that some researchers are working on developing a "DCA-caffeine" cancer treatment protocol.
Now that you're aware of DCA's cancer-fighting effects, let's take a look at the adverse effects identified thus far.
DCA is not a natural agent—it's a chemical produced in the water chlorination process. It's a small molecule, which accounts for one of its major advantages: DCA is easily absorbed by your body and can reach areas other drugs can't, such as your brain, which is why it's of particular interest for treating brain cancers. This, however, can be a two-edged sword, because any compound that easily permeates your brain can exert all sorts of unexpected and worrisome neurological effects.
DCA is a byproduct of another chemical called trichloroethylene (TCE), a volatile organic compound believed to cause cancer. TCE is used mainly as a solvent to remove grease from metal parts, but is also used in adhesives, paint removers, and typewriter correction fluids. The Agency for Toxic Substances and Disease Registry reports TCE is "reasonably anticipated to be a human carcinogen" and may cause birth defects. They state TCE may also cause the following17:
- Skin rashes
- Nerve, kidney, and liver damage
- Impaired heart and immune function
- Unconsciousness
- Death
When DCA is added to the drinking water of laboratory mice, it causes liver cancer. While DCA may offer hope and a novel approach to treating cancer, it is far from a "miracle cure." Of course, chemotherapy drugs are quite toxic as well!
DCA has been used successfully in children with metabolic disorders, with no signs of toxic poisoning. But adults appear to suffer more adverse effects—especially peripheral neuropathy and encephalopathy, such as the case described in a letter to the editor of the Journal of Neurology18. According to a survey performed by The DCA Site19, there are a fair number of serious side effects reported by those taking DCA, many of them neurological. Research suggests the side effects are at least somewhat dose-dependent, but safe dosing guidelines have not yet been established.
In the online survey, the side effects reported by DCA users include:
Tingling and numbness in the fingers, toes and lips; peripheral neuropathy
Leg weakness
Hand tremors
Ankle swelling
Increased urinationMild nausea
Anxiety and depression
Dizziness
Sleepiness
Breathing "heavier" than usualIn some studies, under some circumstances, DCA seems to actually make cancer cells stronger. For example, an in-vitro animal study20 published in May 2010 revealed that some types of colon cancer cells are actually protected by DCA when grown under anoxic conditions or as xenografts in mice (xenografts are tissues transplanted into one species from a dissimilar species). And when DCA is combined with frontline drugs, it sometimes interferes with their effectiveness. The neurological side effects are compounded when DCA is used with other anti-cancer drugs, which are also neurotoxic.
So, if you're already using a cancer medication, DCA's effects are going to be unpredictable and potentially dangerous. This underscores the importance of fully understanding the mechanisms of action of an agent before it enters clinical trials.
What if there were natural agents that induced cancer cell suicide, without the side effects of DCA? As it turns out, these agents DO exist—and you may already have some in your kitchen pantry or supplement cabinet. Here are a few21:
- Co-Q10/Ubiquinol
- Curcumin (the active agent in the spice turmeric)
- Capsaicin (the compound that makes hot peppers hot)
- Se-methylselenocysteine aka methylselenocysteine (found in garlic and broccoli)
- Ellagic acid (from pomegranates and other fruits)
There are many all-natural cancer-prevention strategies, and research shows they may cut your risk in half. Consequently, by implementing multiple strategies, you can radically lower your risk of cancer as well as other chronic diseases.
A healthful lifestyle encourages proper gene expression, as the science of epigenetics has shown. We now know you are in control of your genes, instead of being controlled by them. You actually have tremendous power to shape and direct your health! Your thoughts, your environmental exposures, and your food choices all directly affect your gene expression.
The best "cancer cure" is to prevent it from taking hold in the first place. Cancer cells are circulating in everyone, all the time. The stronger your immune system is, the less likely your cellular function will run amok. Your diet is extremely important in keeping your immune system strong. One of the primary cancer-promoters is sugar. Cancer cells love sugar and use it to fuel their rapid proliferation (by glycolysis, as discussed earlier). This includes ALL forms of sugar, including fructose and grains. The higher your blood glucose level, the more prolific the cancer cells will be.
According to breast cancer expert, author, and board certified surgeon Dr. Christine Horner:
"To me, sugar has no redeeming value at all, because they found that the more we consume it, the more we're fuelling every single chronic disease," Dr. Horner says. "In fact, there was a study done about a year ago… and the conclusion was that sugar is a universal mechanism for chronic disease. It kicks up inflammation. It kicks up oxygen free radicals. Those are the two main processes we see that underlie any single chronic disorder, including cancers. It fuels the growth of breast cancers, because glucose is cancer's favorite food. The more you consume, the faster it grows."
Your diet is the one of the best ways to either feed or prevent cancer. Processed foods, soft drinks, red meat from CAFO-raised animals, trans fats, and any food containing or contaminated with xenoestrogens promote cancer growth. Plant foods, particularly cruciferous vegetables and flax seeds, as well as many herbs and spices are cancer-preventive. Beneficial fats of particular importance for cancer prevention are omega-3 and omega-9, which effectively slow down tumor growth in estrogen-sensitive cancers, such as those of the breast, prostate and colon.
Generally speaking, your diet should focus on fresh, whole, unprocessed foods (vegetables, meats, raw dairy, nuts, and so forth) that come from healthy, sustainable, local sources, such as small organic farms. For the highest nutrient content, you will want to make raw food a significant portion of your diet.
Personally, I aim to eat about 80 to 85 percent of my food raw, including raw eggs and humanely raised organic animal products that have not been raised on a CAFO (confined animal feeding operation).
For more information about which foods to eat and which to avoid, please consult my comprehensive nutrition plan.
There's overwhelming evidence pointing to the fact that vitamin D deficiency plays a roll in cancer development. If there were something close to a silver bullet for cancer, vitamin D would be it.
If you currently have cancer, evidence shows that higher blood levels of vitamin D—probably around 80-90 ng/ml—are beneficial. If natural sun exposure is not practical, then a safe tanning bed or oral supplement are the next best things. Just keep in mind that it's BEST to get your vitamin D from natural sun exposure. It appears vitamin D may play an important role in sulfur metabolism, and taking it orally may not provide the same benefit as deriving it from the sun. To learn the details about how to optimize your vitamin D, including dosage and blood testing, please review our comprehensive vitamin D article.
Vitamin D has been found to offer protection from cancer by several mechanisms, including:
- Regulating genetic expression
- Increasing apoptosis of defective, mutant cells thereby reducing cancer cell replication
- Causing cells to become differentiated (cancer cells often lack differentiation)
- Choking off the growth of new blood vessels from pre-existing ones, which is a step in the transition of dormant tumors turning cancerous
If you are like most people, when you think of reducing your risk of cancer, exercise doesn't immediately come to mind. However, there is some fairly compelling evidence that exercise can slash your cancer risk. One of the primary ways exercise lowers your risk for cancer is by reducing elevated insulin levels, which creates a low sugar environment—and remember, cancer cells LOVE sugar! Additionally, exercise improves the circulation of immune cells in your blood. Consider integrating exercise with intermittent fasting to greatly catalyze your healing and rejuvenation.
Getting proper sleep is critical, both in terms of getting enough sleep and sleeping during the right hours. According to Ayurvedic medicine, the ideal sleeping hours are between 10 pm and 6 am. Modern research has confirmed the value of this recommendation as certain hormonal fluctuations occur throughout the day and night, and if you engage in the appropriate activities during those times, you'll "ride the wave," so to speak. Working against your biology by staying awake when you should be sleeping, or vice versa, interferes with these natural hormone rhythms.
Research tells us that if you experience a traumatic or highly stressful event, such as a death in the family or loss of a job, your risk of breast cancer is 12 times higher in the five years that follows. It is imperative to your health and longevity that you address your emotional well-being. Stress has a direct impact on inflammation, and inflammation drives many of the chronic diseases that kill people prematurely every day.
Meditation, prayer, yoga, and EFT (an energy psychology tool) are all viable options that can help you maintain emotional/psychological equilibrium. I'm sure you can think of others—the bottom line is, find what works best to de-stress yourself and practice it daily.
Just as stress is toxic to your emotional health, chemical overload is toxic to your physical health, and both can weaken your immune system. Get rid of as much toxic junk as you can. This includes harsh chemical household cleaners, soaps, personal hygiene products, air fresheners, bug sprays, lawn pesticides, insecticides and the rest. Replace them all with green, non-toxic alternatives.
For more suggestions about how to prevent and heal from cancer, please refer to the cancer section of our website, which contains a wealth of free, research-based information. 12
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The day after Mother’s Day is Men for Women Now Day… A day to encourage all women to make their appointments for mammograms add pap smears.
Go to: http://www.noreenfraserfoundation.org/ and send someone you love a celebrity Mother’s Day Card and reminder.
The mission of the Noreen Fraser Foundation (NFF) is to raise funds for women’s cancer research. NFF supports translational cancer research aimed at developing new prevention methods, diagnostic tools and non-toxic therapies to treat women’s cancers. Our hope is that until there are CURES, women’s cancers will become manageable diseases controlled with targeted therapies that protect patients’ quality of life. The Noreen Fraser Foundation is a 501(c)(3) tax exempt organization
Canadian researchers find a simple cure for cancer, but major pharmaceutical companies are not interested.
Researchers at the University of Alberta, in Edmonton, Canada have recently cured cancer, yet there is but little ripple in the news or on TV. It is a simple technique using a very basic drug. The method employs dichloroacetate, which is currently used to treat metabolic disorders, so there is no concern of side effects or other long term effects.
The drug doesn’t require a patent, so anyone can employ it widely and cheaply compared to the costly cancer drugs produced by major pharmaceutical companies.
Canadian scientists tested dichloroacetate (DCA) on human cells; it killed lung, breast and brain cancer cells and left the healthy cells alone. It was tested on rats inflicted with severe tumors; their cells shrank when they were fed with water supplemented with DCA. The drug is widely available and the technique is easy to use, but why are the major drug companies not involved, or the media not interested in this find?
In human cells there is a natural cancer fighting organelle, the mitochondria, but it needs to be triggered in order to be effective. Scientists used to think that the mitochondria of cancerous cells were damaged and thus ineffective. They used to focus on glycolysis, which is less effective in fighting cancer and wasteful. The drug manufacturers focused on the glycolysis method to fight cancer. DCA treatment on the other hand doesn’t rely on glycolysis but instead on reactivating the mitochondria; which allows the cell to die and preventing the cancer from spreading.
This reactivation is a process called apoptosis. You see, mitochondria contain an all-too-important self-destruct button that cannot be pressed in cancer cells. Without it, tumors grow larger as cells refuse to be extinguished. Fully functioning mitochondria, thanks to DCA, can once again allow them to die.
With glycolysis turned off, the body produces less lactic acid, so the bad tissue around cancer cells doesn’t break down and seed new tumors.
Pharmaceutical companies are not investing in this research because DCA method cannot be patented, and without a patent they cannot make money. They’re currently making fortunes with their AIDS patent. Since the pharmaceutical companies won’t develop DCA drugs, independent laboratories should start researching DCA more to confirm all of the above findings and begin producing drugs. All of the groundwork can be done in collaboration with the universities, who will be glad to assist in such research and can develop an effective drug for curing cancer.
This article hopes to raise more awareness of dichloroacetate, and to hopefully inspire some independent companies and small startups to pick up on this idea and begin producing life-saving drugs… because the big companies won’t be touching it for a long time.
Posted on January 27, 2012 by Gekko - Money Trends Research ^