New MRSA Strain That Eludes Usual Tests Found in Cow’s Milk

British scientists have discovered a new strain of the drug-resistant germ known as MRSA in cow’s milk and some evidence that the animals could be a source of the infection in humans.

University of Cambridge researchers were led to the discovery while studying an infection of the animals’ udders, according to an article published today in the U.K journal The Lancet Infectious Diseases.Tests showed that people in Scotland, England and Denmark carried the new variant of MRSA, or methicillin-resistant Staphylococcus aureus, and that the bacteria can elude the usual means of detection.

Tests that search for the mecA gene, which enables the bacteria to resist treatment with some antibiotics, can miss the new, genetically different strain, researchers said. Relying solely on gene testing can lead doctors to prescribe medicines that are powerless against MRSA, the researchers said.

“It’s important that any of the MRSA testing that is based on detection of the mecA gene be upgraded to ensure that the tests detect the new gene found in the new MRSA,” said Mark Holmes, the lead researcher, in a statement.

While the new strain can cause disease in people, the risk of becoming infected is low, the scientists said. Further study is planned to determine how prevalent the new strain is and where it’s coming from, the researchers said.

Molecular Testing

Standard molecular screening for MRSA searches for the mecA gene. The new strain has a mecA gene that’s only 60 percent similar to the original version, leading to a false negative result when tested, the study found.

Testing should be updated to identify the genetic change, researchers said. The majority of testing in British hospitals is performed by seeing if the bacteria will grow in the presence of antibiotics, Holmes said.

“Even though this new strain isn’t picked up by the current molecular tests, they do still remain effective for the detection of over 99 percent of MRSAs,” said Angela Kearns, head of the U.K. Health Protection Agency’s Staphylococcus Reference Laboratory, in a statement.

The researchers also found evidence that cattle could be a key reservoir of the new strain of MRSA. The samples found in humans were either of a strain thought to be unique to animals or other types detected in cattle, the study said. In England, the researchers found a geographical association between human and animal isolates of MRSA. Pasteurization of milk will prevent infection, they said.

Staphylococcus aureas bacteria live on the skin and in nasal passages. Of the people with the bacteria present, about 1 percent have MRSA, according to the U.S. Centers for Disease Control and Prevention. MRSA causes infection when germs enters the body through a cut, a sore, a catheter or a breathing tube, according to the U.S. National Institutes of Health.

MRSA Infections

MRSA infections can occur in hospitals or in otherwise healthy people who come into contact with the bacteria in settings such as locker rooms or daycare centers, the NIH said. Infections cause a red, painful, swollen area on the skin, and symptoms of severe cases include chest pain, chills, fatigue, fever and shortness of breath.

Serious MRSA infections acquired while in the hospital may be treated with medicines including Cubist Pharmaceuticals Inc. (CBST)’s Cubicin, Pfizer Inc.’s Zyvox and generic drugs such as doxycycline and tetracycline, according to NIH.

To contact the reporter on this story: Kristen Hallam in London at khallam@bloomberg.net

To contact the editor responsible for this story: Phil Serafino at pserafino@bloomberg.net

Beat Prostate Cancer Naturally

At some point in life, about one in six American men will be diagnosed with prostate cancer, which is second only to lung cancer among the leading causes of cancer deaths in men.

Scientists are just beginning to understand that inflammation may play a key role in prostate cancer’s development, but they have found that the degree of inflammation may play a huge role in survival chances. Men with prostate cancer who have higher levels of inflammatory chemicals have poorer prognoses than those with lower levels, researchers say.

The inflammation may be too subtle for a doctor to pick up, but obvious inflammatory conditions have been present for decades in a majority of cases. For example, one might have chronic prostatitis for 15-20 years before prostate cancer develops. 

Most cancer researchers believe the most common risk to developing cancer is age. The older we get, the more likely we are to develop a cancer. As we age, our bodies become more inflamed, and those with the greatest inflammation are at the greatest risk of cancer.

As we age, our DNA becomes damaged and our bodies become less able to repair it. That’s when a healthy diet is especially vital. Diets are a major factor in the chances of developing prostate cancer. Scientific evidence indicates that a diet high in vegetable oils, red meats, trans fats, and sugar, but low in selenium, natural vitamin E, zinc, and lycopene greatly increases a man’s risk.

But special nutrients and nutrient combinations help fight prostate cancer. They include:

• Selenium. One double-blind study found that selenium supplementation reduced prostate cancer by 63 percent.
• Vitamin E. In one study, men with the highest gamma-vitamin E had a five-fold reduction in prostate cancer risk.
• Quercetin. This nutrient found in onions dramatically reduces inflammation in the prostate gland and protects DNA
• Cucurmin. Found in the Indian spice turmeric, curcurmin curtails the growth of prostate cancers.
• Lycopene. A powerful anti-inflammatory, it’s the pigment that gives tomatoes their red color.
• Indole-3 carbinol. A broccoli extract that can reduce a swollen, inflamed prostate dramatically when combined with lycopene.

One study found that the most common link to prostate cancer was the consumption of milk, especially non-fat milk. In fact, more than two-thirds of cases were attributed to milk consumption. The reason appears to be high amounts of calcium, since taking calcium supplements also dramatically increased risk.

Other studies have shown that diets containing more than 2,000 milligrams of calcium a day (from all sources) dramatically increase the number of advanced prostate cancers when compared with diets containing fewer than 500 milligrams.

There is also a strong correlation between calories from sugars and carbohydrates and the early development of prostate cancer. High caloric intake increased risk 267 percent in one study. This is a significant risk factor because Americans consume tremendous amounts of sugar.

You can take many to reduce the risk of developing prostate cancer. If you combine all of the factors that we know, you can make your risk of developing prostate cancer extremely low.