Showing posts with label Oxidative Stress. Show all posts
Showing posts with label Oxidative Stress. Show all posts

Thursday, May 2, 2013

You Knew It Was Coming… First Vaccine Announced For Autism

By Dave Mihalovic, Prevent Disease - Waking Times – h/t to MJ

vaccine needlesA first-ever vaccine created by University of Guelph researchers to control autistic symptoms is here. The medical propaganda matrix has once again come full circle with their patented problem-reaction-solution. Although there is no study which directly links vaccines as the cause of autism, there have been hundreds of others with correlations. Even if scientists are dismissive on the causation front, why do they continue to explore methods which are misinformed, misguided and completely ineffective?

Constipation and diarrhea are common in autistic patients. So what’s the solution? A vaccine of course.

Physicians bombard autistic children with antibiotics for a bacteria Clostridium bolteae that has been shown in overabundance in the intestinal tract of autistic children suffering from gastric intestinal ailments.

Some research has noted that an autism-associated neurotoxin produced by Clostridium bolteae may play a role in triggering late-onset autism in some individuals.

The study by Brittany Pequegnat and Guelph University chemistry professor Mario Monteiro appears this month in the journal Vaccine.

They developed a carbohydrate-based vaccine against the bacteria.

What is particularly interesting about this vaccine is that researchers know practically nothing about why autistic children have higher concentrations of the bacteria, or whether or not it specifically causes the range of gastrointestinal distress these children experience. “Little is known about the factors that predispose autistic children to C. bolteae,” said Monteiro. Although most infections are handled by some antibiotics, he said, a vaccine would improve current treatment.

Diet and prescription medication has long been suspected as causes for the increase in C. bolteae, however researchers seem the glance over the data in favor of vaccine development.

“This is the first vaccine designed to control constipation and diarrhea caused by C. bolteae and perhaps control autism-related symptoms associated with this microbe,” he said.

The U.S. Centers for Disease Control (CDC) estimates that there are now 1 in 88 children in the United States who have autism spectrum disorder (ASD). Boys are almost five times more likely to be autistic than girls — with 1 in 54 boys now identified. This represents almost a 1000% increase since the 1980s.

There have never been any long term, double blind studies for any vaccine to prove that they are not responsible for the development of autism in children. The vaccine testing, therefore, is on the general population.

Although many scientists have focused on vaccines, environmental factors and genetics, others have applied their research to the human gut.

Some researchers believe toxins and/or metabolites produced by gut bacteria, including C. bolteae, may be associated with symptoms and severity of autism, especially regressive autism.

The new anti- C. bolteae vaccine supposedly targets the specific complex polysaccharides, or carbohydrates, on the surface of the bug. There is no currently no evidence in any trials that the vaccine has effectiveness to curb symptoms of autism or GI distress.

The vaccine might take more than 10 years to work through pre-clinical and human trials, and it may take even longer before a drug is ready for market, Monteiro said.

“But this is a significant first step in the design of a multivalent vaccine against several autism-related gut bacteria,” he said.

Why Additional Vaccines Are Not The Answer

The reason vaccines will never address the underlying problems related to autism and GI distress is due to the reactions of specific pollutants of which autistic children experience negative symptoms. The highest probable cause for C. bolteae’s abundance is due to an imbalance of bacterial populations in the gut which are attempting to balance the stress from these pollutants.

Many parents have claimed a high degree of success from dietary strategies to reduce the symptoms of autistic spectrum disorder (ASD). According to researchers from Penn State a gluten-free, casein-free diet may lead to improvements in behavior and physiological symptoms in children diagnosed with autistic spectrum disorder ASD.

“Research has shown that children with ASD commonly have GI [gastrointestinal] symptoms,” said Christine Pennesi, medical student at Penn State College of Medicine. “Notably, a greater proportion of our study population reported GI and allergy symptoms than what is seen in the general pediatric population. Some experts have suggested that gluten- and casein-derived peptides cause an immune response in children with ASD, and others have proposed that the peptides could trigger GI symptoms and behavioral problems.”

“Gluten and casein seem to be the most immunoreactive,” Klein said. “A child’s skin and blood tests for gluten and casein allergies can be negative, but the child still can have a localized immune response in the gut that can lead to behavioral and psychological symptoms. When you add that in with autism you can get an exacerbation of effects.”

“If parents are going to try a gluten-free, casein-free diet with their children, they really need to stick to it in order to receive the possible benefits,” she said.

Detoxification and Immune Systems

In the body of an autistic individual, portions of the detoxification system, as well as specific metabolic processes become dysfunctional, leading to a diminished ability to completely break down certain foods. When analyzed by sophisticated scientific instruments, a portion of these partially digested substances are shown to resemble morphine (yes, morphine). These neurotoxins (opioid substances) leak out of the digestive tract, into the blood stream and attack the brain/nervous system, producing the symptoms and complications associated with autism. Diminished levels of critical substances such as glutathione (resulting in oxidative stress) keep this process in place.

Recovery of autism requires:

- Stop the production of neurotoxins (opioid substances)

- Reduce or eliminate oxidative stress

- Heal the nervous system

In October of 2001, a team of clinicians and researchers led by William Walsh, Ph.D. then at the Pheiffer Treatment Center, affiliated with the Health Research Institute now of Warrenville, IL, made available a scientific study entitled “Metallothionein and Autism”. Metallothionein is a protein that is critical to the process of detoxification of harmful substances, particularly heavy metals and toxic chemicals.

The paper describes a study of 503 patients on the autism spectrum vs. aged-matched non-autistic patients. The conclusion of this study was that “most autistic patients exhibit evidence of metallothionein (MT) dysfunction and this dysfunction may be a universal characteristic of autism-spectrum disorders”.

Translation: the detox systems of autistics are impaired.

Walsh also concluded that “MT dysfunction and autism may result from the intersection of two factors: (a) a genetic defect involving marginal or defective MT functioning, followed by (b) an environmental insult during early development which disables MT.”

According to Walsh’s paper, once MT becomes compromised, a host of other dysfunctions occur, including:

-Detoxification of mercury and other toxic metals

-Development and functioning of the immune system

-Development and paring of brain neurons

-Regulation of zinc and copper levels in blood

-Prevention of yeast overgrowth in the intestines

-Production of enzymes that break down casein and gluten

-Response to intestinal inflammation

-Production of stomach acid

-Taste and texture discrimination of tongue epithelia

-Hippocampus function and behavior control

-Development of emotional memory

Walsh’s paper continues: “Examples of biochemical factors which can disable MT proteins include (a) severe zinc depletion, (b) abnormalities in the glutathione redox system, (c) cysteine deficiency, and (d) malfunction of metal regulating elements (MRE’s).”

Glutathione is frequently mentioned in biomedical discussions of autism due to its critical role in the detoxification pathway. Glutathione is produced by a metabolic process known as the methionine cycle. Important work has been performed describing the most vulnerable parts of the methionine cycle. This cycle starts with methionine and is supposed to end with glutathione. However, because this metabolic process has been disrupted in autistics, little or no glutathione is produced. Indeed, oxidative stress, or low levels of glutathione have been described as a hallmark traits of autism.

Because glutathione is so critical in the detoxification pathway, diminished levels begin to interfere with a variety of other metabolic processes as initially described by Dr. Walsh and borne out via subsequent research. These include the dysfunction of the methylation and sulfation processes. Following is an excerpt from “Autism is Curable. How a Generation Was Poisoned And How To Correct It” by Dr. Stuart H Freedenfeld describing these processes.

“Methylation is an extremely important process that is essential to our health. It activates brain-signaling molecules and inactivates DNA and RNA (it is how liver cells learn to be different from muscle cells and how we inactivate viruses). Impairment of the methylation mechanism impairs another process called sulfation. Sulfation is necessary to produce many substances including the protective coating of the digestive tract and the connective tissues of the body. It is also the source of the most important detoxifying substance in our body, glutathione. This substance is so important that if its level falls below a certain amount in any cell, that cell will self-destruct. Glutathione is also the essential mechanism to remove toxic metals from inside the cells.

The Neurological System

Imagine for a moment the impact of having a dose of morphine delivered into your bloodstream and brain after every meal, day in and day out. Now observe the way an autistic child or adult behaves. Is it possible that they have been living under the burden of a highly potent and destructive opioid neurotoxin on a daily basis for a large portion of their lives?

Following are quotes from “Unraveling the Mystery of Autism and Pervasive Developmental Disorder: A Mother’s Story of Research & Recovery” by Karyn Seroussi, which beautifully describes the recovery of her son from autism via diet. “…these opiates, if they are permitted to enter the brain, can have a widespread effect on the nervous system similar to that of hallucinogenic drugs; and this results, in a developing child’s brain, in autistic behaviors. The proof of this lies in the presence of such drugs in the urine of the autistic children.

These effects will include disrupting neurotransmission in all the main systems (dopamine, serotonin, GABA, etc.). Consequently, perceptions by all of the senses (hearing, sight, taste, proprioception, pain, etc.) will be affected to a varying degree. At the same time, so will the ability to filter out what is important from what is not.” From “Unravelling the Mysteries of Autism and Pervasive Developmental Disorder” by Karyn Seroussi.

Other evidence that morphine-like substances are reaching the brain is the frequent observation that autistics tend to crave and eat the same food, dairy and wheat based, all the time. Mac and cheese. Pizza. They appear to be addicted to their own food. They fly into fits when they don’t get it. Once they eat it they appear to lapse into a “food coma” until the addiction once again overwhelms them and they demand more.

Other observed neurological manifestations could be the result of opioids reaching the brain include seizures and changes to brain structure observed on imaging studies. But the real proof is in the ability to reverse the processes causing these symptoms resulting in improvement and recovery.

Recovery from autism:

(1) Stop production of opioid neurotoxins

(2) Reduce or eliminate oxidative stress

(3) Heal the nervous system

Knowing the metabolic processes at play that result in the symptoms of autism, one can begin to envision that reversal of these processes could lead to recovery or at least diminishment of symptoms. This is exactly what happened with recovered autistics.

Stop the production of Opioid Neurotoxins and Reduce or Eliminate Oxidative Stress (Yes, these can sometimes be addressed with the same treatment methods):

Treating autism with vaccines is only adding fuel to the fire in terms of exacerbating symptoms that could otherwise be reduced or eliminated through dietary and detoxification strategies. The medical community continues its arrogance and ignorance in adopting treatment protocols that have a higher probability of harming rather than helping patients. The key for all ASD affected children is to seek healing through natural intervention which address inflammatory, oxidative and immunotoxic stress as the primary course of action.

About the Author  -  Dave Mihalovic is a Naturopathic Doctor who specializes in vaccine research, cancer prevention and a natural approach to treatment.

Comments:

AJ:  Sheesh!  Haven't they harmed enough kids already? 

Related:

Book: Vaccination Is Not Immunization 3rd Ed. Third Edition (2013)

Autism Epidemic

83 percent of brain injury vaccine compensation payouts were for autism caused by vaccines

78 percent increase in autism rates over past decade coincides with new vaccination schedules

Robert F. Kennedy Jr. Tells Truth About Government Cover-up of Vaccine Dangers

What It's Like to Have Autism

The Hoax at the Bottom of Autism and Alzheimer’s

Myth Busted: Vaccinations Are Not Immunizations

"The" Dr. Oz Bait for Vaccine: Why Did He Do It?? Oz Kids and Wife Not Getting H1N1

First Daughters Not Vaccinated Against H1N1

Thursday, November 26, 2009

Dr. Mercola: How Trillions of Dollars Were Stolen From U.S. Taxpayers

Posted by: Dr. Mercola
November 26 2009 | 1,656 views

An offshore corporate cartel is bankrupting the U.S. economy -- by design. Could it be that a worldwide regime, controlled by an unelected corporate elite, is implementing a system that will dominate all human activity and establish a system of neo-feudal slavery?

Watch the Fall of the Republic, and decide for yourself.

You may ask yourself... why is this being posted on a health site?!? The answer is that it all ties together and that often not knowing causes more stress than knowing the enemy so we can fight back together!!

Dr. Mercola's Comments:

The Fall of the Republic, another critical-eye documentary by Alex Jones, offers a sobering glimpse behind the curtain of American politics and the international banking system.

It is a shocking expose of how the US got into the mess we’re now in, and just how dire our situation may yet become if we don’t act swiftly and decisively to do the right thing for our nation.

I particularly enjoyed the former secretary of the treasury, Henry Paulson’s, testimony before Congress. I don’t recall ever seeing anyone more blatantly lying about something he was trying to cover up, using flimsy excuse after flimsy excuse to justify his behavior. Absolutely despicable behavior...

But the US financial system is not the only thing that needs to be carefully reviewed and overhauled.

Why Does a Health Site Comment on the Economy?

You might wonder why I am posting this information on a health site. Well some people simply fail to appreciate the obvious, so let me spell it out for those who believe it to be inappropriate for me to review this material.

Emotions are, without question, the single largest contributor to your health. One out of four people in the US are out of work and the financial future of many seems very bleak. Heck, 15 percent of the US population doesn’t even have enough money to buy enough processed (unhealthy) food to keep them out of hunger. This creates strong negative emotions in most that will inevitably deteriorate their health.

That is the obvious connection, but additionally many will not have the funds to purchase high quality foods, or pay for the invariable medical expenses that they encounter if they don’t.

It is also obvious that accidents happen. And when they do they can generate large medical bills, which are the number one reason for having to declare bankruptcy in the US.

So there are many ways in which political happenings can be related to health.

Did you know that according to a recent 60 Minutes story, the government run Medicare loses $60 billion of your tax dollars to fraud, every year. Just think what it will be if they run 1/6 of our economy and all medical decisions.

Health Care Reform

Additionally, we’re currently in the middle of heated debates about health care reform, which may end up making or breaking more than the health of American citizens. It will have enormous ramifications for the future of the US economy.

One of the major reasons for the support of a government run health care plan is due to the belief that government run programs, like Medicare, have lower administrative costs than private plans.

However, as Robert Samuelson with the Washington Post has noted, that is simply not true. On a per person basis, Medicare actually has higher administrative costs than the private sector.

More importantly, the private sector does a much better job rooting out fraud and waste than the government does. As a potent example, watch the 60 Minutes story (second video above), which details how Medicare fraud costs US taxpayers a staggering$60 billion a year!

For more examples, just use the search word “medicare” to search my site, and you’ll find a number of articles written throughout the years, highlighting the problem of widespread Medicare fraud.

Back in 2007, I posted a video of the US Comptroller General, who warned that funding shortfalls for the Medicare program were five times worse than Social Security, and that it would take $8 trillion to pay for what is promised to beneficiaries, of which we had, and still have, ZERO!

When Medicare was introduced by President Johnson in 1965, it was a classic example of the devastating complications that can result from well-intentioned government intervention in our health care system. Now, more than 40 years later, it has become clear that Medicare is a prescription for financial disaster.

What makes anyone think that adding more government run health care plans will change this situation for the better?

YOU Are the Solution

The majority of the American public is clueless when it comes to health. They have been effectively manipulated and deceived by the brilliant marketing scams of drug companies.

Offering government run health care programs that do absolutely nothing to change the current medical paradigm, by focusing solely on trying to figure out how to continue paying for unnecessary drugs and surgical procedures is not the answer.

It is time to stand up, and not only voice your own opinions to your elected representatives, but also take control of your own health.

Take Control of Your Health

Start engaging in behaviors that allow you to become independently healthy so you don't have to rely on whatever drug-company solutions may be offered.

If you can lead by example you can be a pillar of light out of this darkness we have progressed into.

All we need to do is convince 10 percent of the population, and this system will crumble.

You can start by following the principles I have outlined in my comprehensive nutrition program. This comprehensive program is divided into beginner, intermediate and advanced sections so you can step in wherever your current health level commitment is.

You can then engage in a comprehensive exercise program, which will further move you towards health and keep you protected from illness.

It is important to remember that no synthetic drug or chemical will ever address the underlying cause of your illness. By adopting healthy lifestyle changes you will be able to build resistance to just about every disease that might cause physical harm.




Monday, November 27, 2006

Oxidative Stress

Even though the average life expectancy in the United States has increased dramatically during this past century, our quality of life due to chronic degenerative disease has taken a major hit. We are essentially "living too short and dying too long". Most of us can simply look forward to suffering and dying from heart disease, cancer, stroke, diabetes, Alzheimer’s dementia, Parkinson’s disease, arthritis, macular degeneration, and the list goes on and on, unless we literally attack the underlying cause of all of these diseases—oxidative stress.

How long do you expect to live? Now envision what your last twenty years will look like. I can assure you my patients today are not as concerned with the number of years in their lives as they are the quality of life in those years. Who wants to live to a ripe old age if he or she cannot even recognize close family members because of Alzheimer’s dementia? Who looks forward to a decade or two of suffering severe joint or back pain due to degenerative arthritis?

One of my close friends told me recently that he simply wants to live until he dies. Is this your desire? It certainly is mine. That is why I recommend preventative rather than post-problem medicine--empowering people to avoid getting major diseases in the first place. Over the past seven years, I have changed my approach. I now strongly encourage and support my patients in taking a three-fold approach to health: eating well, practicing a consistent exercise program, and daily consuming high-quality nutritional supplements. I now use medication as a last resort—not as my first choice.

Do you fear growing old? Have you accepted chronic disease or pain as a given in your future? Are you willing to make necessary life changes to ensure your health? I believe a full and abundant physical life does not need to start slipping away at age forty. Each year of your life can be your very best. But first you must understand the war that is waging within every one of our bodies.

Oxygen is essential for life itself. But did you know it is also inherently dangerous to our existence? I call this the "dark-side" of oxygen. And as a result, we are essentially rusting both inside and out. The same process that causes a cut apple to turn brown or iron to rust is the cause of all the chronic degenerative diseases we fear and even the aging process itself.

Consider the aging of our skin. Oxidative stress is the cause of wrinkles, sagging skin, and age spots. The next time you are with a large gathering of people of different ages, observe closely the change you see in people’s skin. Aging is a process we all take for granted, but when you look more closely, and compare a baby’s face, to that of a grandparent’s, the effects of our largest organ being exposed to all the pollutants in the air, sunlight, and cigarette smoke is baffling. This aging of the skin is an outward manifestation of "oxidative stress," which is occurring within every cell in your body.

Over the past 7 years, I have reviewed well over 2,000 medical and scientific studies in regards to nutritional supplements and their affect on your health. These studies appearing in medical journals like the New England Journal of Medicine, Journal of the American Medical Association, British Lancet, and Annuals of Internal Medicine report that beyond any doubt the "root" cause of well over 70 chronic degenerative diseases is "oxidative stress." These are the "who’s who" of diseases we all fear and want to avoid; diseases like heart attacks, strokes, diabetes, cancer, arthritis, Alzheimer’s dementia, macular degeneration, lupus, MS, fibromyalgia, and chronic fatigue. "So what," you may be wondering, "is ‘oxidative stress’?"

Within every cell of the body is a furnace called the mitochondria. As oxygen is utilized within the furnace of the cell to create energy and life itself, occasionally a charged oxygen molecule is created, called a "free radical." This free radical has at least one unpaired electron in its outer orbit essentially giving it an electrical charge. If this free radical is not readily neutralized by an antioxidant it can go on to create more volatile free radicals, damage the cell wall, vessel wall, proteins, fats, and even the DNA nucleus of our cells. Chemically this reaction has been shown to be so volatile that it actually causes bursts of light within our bodies!

Imagine yourself in front of a crackling fireplace and I’ll give you the best illustration I have to explain the process of oxidation. The fire burns safely and beautifully most of the time, but on occasion out pops a hot cinder that lands on your carpet and burns a little hole in it. One cinder by itself doesn’t pose much of a threat; but if this sparking and popping continues month after month, year after year, you will have a pretty "ratty" carpet in front of your fireplace.

The fireplace represents the furnace of the cell (the mitochondria), the cinder is the charged "free radical," and the carpet is your body. Whichever part of your body receives the most free radical damage will be the first to wear out and potentially cause one of these degenerative diseases. If it’s your arteries, you could develop a heart attack or stroke. If it is your brain, you could develop Alzheimer’s dementia or Parkinson’s disease. If it’s your joints, you could develop arthritis.

Through biochemical research we’re learning that we are not defenseless against this attack on our body by free radicals. Antioxidants are like the glass doors or fine-wire mesh we place in front of our fireplace. The sparks are still going to fly but our carpet will then be protected. As you begin to imagine the war that is taking place within every cell in your body, you can envision the two opposing forces: the enemy--free radicals; and your allies--antioxidants and their supporting nutrients.

Living a healthy life becomes a matter of balance. You must have enough antioxidants available to readily neutralize the number of free radicals your body produces. If you don’t, "oxidative stress" will occur. When this oxidative stress is allowed to persist over a prolonged period of time, you will most likely develop a serious chronic degenerative disease.

Each of us must ask, "Am I getting enough antioxidants from my diet to protect myself from this onslaught of free radicals or do I need to be taking nutritional supplements?" This is the question that I’ve had to ask myself as I have spent countless hours researching medical literature. You see I was taught in medical school that you don’t need supplements—that you can get everything you need from a good, healthy diet. And this is what I told my patients for years. I was wrong.

Since balance is the key, we need to look closely at the individual players that are at war within. The number of free radicals you produce each and every day is never the same. All the pollutants in our air, food, and water dramatically increase the number of free radicals we produce. Enormous stress, excessive exercise, cigarette smoke, sunlight, radiation, and every drug prescribed greatly increases the number of free radicals produced in the body. In fact, there has never been a generation on this planet subjected to more oxidative stress than this present one. We are literally under attack from our polluted environment, stressful lifestyles, and over-medicated society.

This ongoing attack is depriving us of our most precious gift—our health. But God did not leave us defenseless against this onslaught by free radicals. In fact, we actually have our own army of antioxidants, which are able to neutralize free radicals and render them harmless. In generations past, these defense systems were sufficient. Unfortunately this is no longer the case. Our bodies’ defense systems need additional allies.

Most antioxidants come from vegetables and fruit. This creates a gap in our protection, because our foods have become significantly depleted in their content of antioxidants and supporting minerals as a result of mineral depletion in our soils, green harvesting, cold storage, foods that are highly processed, our poor food choices and food preparation.

At a time when we are under the heaviest attack from the environment around us, our natural defense systems are becoming overwhelmed and depleted. We must do all we can to rebuild our antioxidant systems with a healthy diet, but too you need to learn how complete and balanced nutritional supplementation with high quality supplements (cellular nutrition) is our best hope in winning this war within and protecting our health.

Source: Dr. Ray Strand