Showing posts with label ADHD drugs. Show all posts
Showing posts with label ADHD drugs. Show all posts

Wednesday, October 10, 2012

Attention Disorder or Not, Pills to Help in School

“We’ve decided as a society that it’s too expensive to modify the kid’s environment. So we have to modify the kid.”

NY Times: CANTON, Ga. — When Dr. Michael Anderson hears about his low-income patients struggling in elementary school, he usually gives them a taste of some powerful medicine: Adderall.’

The pills boost focus and impulse control in children with attention deficit hyperactivity disorder. Although A.D.H.D is the diagnosis Dr. Anderson makes, he calls the disorder “made up” and “an excuse” to prescribe the pills to treat what he considers the children’s true ill — poor academic performance in inadequate schools.

“I don’t have a whole lot of choice,” said Dr. Anderson, a pediatrician for many poor families in Cherokee County, north of Atlanta. “We’ve decided as a society that it’s too expensive to modify the kid’s environment. So we have to modify the kid.”

Dr. Anderson is one of the more outspoken proponents of an idea that is gaining interest among some physicians. They are prescribing stimulants to struggling students in schools starved of extra money — not to treat A.D.H.D., necessarily, but to boost their academic performance.

It is not yet clear whether Dr. Anderson is representative of a widening trend. But some experts note that as wealthy students abuse stimulants to raise already-good grades in colleges and high schools, the medications are being used on low-income elementary school children with faltering grades and parents eager to see them succeed.

“We as a society have been unwilling to invest in very effective nonpharmaceutical interventions for these children and their families,” said Dr. Ramesh Raghavan, a child mental-health services researcher at Washington University in St. Louis and an expert in prescription drug use among low-income children. “We are effectively forcing local community psychiatrists to use the only tool at their disposal, which is psychotropic medications.”

Dr. Nancy Rappaport, a child psychiatrist in Cambridge, Mass., who works primarily with lower-income children and their schools, added: “We are seeing this more and more. We are using a chemical straitjacket instead of doing things that are just as important to also do, sometimes more.”

Dr. Anderson’s instinct, he said, is that of a “social justice thinker” who is “evening the scales a little bit.” He said that the children he sees with academic problems are essentially “mismatched with their environment” — square pegs chafing the round holes of public education. Because their families can rarely afford behavior-based therapies like tutoring and family counseling, he said, medication becomes the most reliable and pragmatic way to redirect the student toward success.

“People who are getting A’s and B’s, I won’t give it to them,” he said. For some parents the pills provide great relief. Jacqueline Williams said she can’t thank Dr. Anderson enough for diagnosing A.D.H.D. in her children — Eric, 15; Chekiara, 14; and Shamya, 11 — and prescribing Concerta, a long-acting stimulant, for them all. She said each was having trouble listening to instructions and concentrating on schoolwork.

“My kids don’t want to take it, but I told them, ‘These are your grades when you’re taking it, this is when you don’t,’ and they understood,” Ms. Williams said, noting that Medicaid covers almost every penny of her doctor and prescription costs.

Some experts see little harm in a responsible physician using A.D.H.D. medications to help a struggling student. Others — even among the many like Dr. Rappaport who praise the use of stimulants as treatment for classic A.D.H.D. — fear that doctors are exposing children to unwarranted physical and psychological risks. Reported side effects of the drugs have included growth suppression, increased blood pressure and, in rare cases, psychotic episodes.

The disorder, which is characterized by severe inattention and impulsivity, is an increasingly common psychiatric diagnosis among American youth: about 9.5 percent of Americans ages 4 to 17 were judged to have it in 2007, or about 5.4 million children, according to the Centers for Disease Control and Prevention.

The reported prevalence of the disorder has risen steadily for more than a decade, with some doctors gratified by its widening recognition but others fearful that the diagnosis, and the drugs to treat it, are handed out too loosely and at the exclusion of nonpharmaceutical therapies.

The Drug Enforcement Administration classifies these medications as Schedule II Controlled Substances because they are particularly addictive. Long-term effects of extended use are not well understood, said many medical experts. Some of them worry that children can become dependent on the medication well into adulthood, long after any A.D.H.D. symptoms can dissipate.

According to guidelines published last year by the American Academy of Pediatrics, physicians should use one of several behavior rating scales, some of which feature dozens of categories, to make sure that a child not only fits criteria for A.D.H.D., but also has no related condition like dyslexia or oppositional defiant disorder, in which intense anger is directed toward authority figures. However, a 2010 study in the Journal of Attention Disorders suggested that at least 20 percent of doctors said they did not follow this protocol when making their A.D.H.D. diagnoses, with many of them following personal instinct.

On the Rocafort family’s kitchen shelf in Ball Ground, Ga., next to the peanut butter and chicken broth, sits a wire basket brimming with bottles of the children’s medications, prescribed by Dr. Anderson: Adderall for Alexis, 12; and Ethan, 9; Risperdal (an antipsychotic for mood stabilization) for Quintn and Perry, both 11; and Clonidine (a sleep aid to counteract the other medications) for all four, taken nightly.

Quintn began taking Adderall for A.D.H.D. about five years ago, when his disruptive school behavior led to calls home and in-school suspensions. He immediately settled down and became a more earnest, attentive student — a little bit more like Perry, who also took Adderall for his A.D.H.D.

When puberty’s chemical maelstrom began at about 10, though, Quintn got into fights at school because, he said, other children were insulting his mother. The problem was, they were not; Quintn was seeing people and hearing voices that were not there, a rare but recognized side effect of Adderall. After Quintn admitted to being suicidal, Dr. Anderson prescribed a week in a local psychiatric hospital, and a switch to Risperdal.

While telling this story, the Rocaforts called Quintn into the kitchen and asked him to describe why he had been given Adderall.

“To help me focus on my school work, my homework, listening to Mom and Dad, and not doing what I used to do to my teachers, to make them mad,” he said. He described the week in the hospital and the effects of Risperdal: “If I don’t take my medicine I’d be having attitudes. I’d be disrespecting my parents. I wouldn’t be like this.”

Despite Quintn’s experience with Adderall, the Rocaforts decided to use it with their 12-year-old daughter, Alexis, and 9-year-old son, Ethan. These children don’t have A.D.H.D., their parents said. The Adderall is merely to help their grades, and because Alexis was, in her father’s words, “a little blah.”

”We’ve seen both sides of the spectrum: we’ve seen positive, we’ve seen negative,” the father, Rocky Rocafort, said. Acknowledging that Alexis’s use of Adderall is “cosmetic,” he added, “If they’re feeling positive, happy, socializing more, and it’s helping them, why wouldn’t you? Why not?”

Dr. William Graf, a pediatrician and child neurologist who serves many poor families in New Haven, said that a family should be able to choose for itself whether Adderall can benefit its non-A.D.H.D. child, and that a physician can ethically prescribe a trial as long as side effects are closely monitored. He expressed concern, however, that the rising use of stimulants in this manner can threaten what he called “the authenticity of development.”

“These children are still in the developmental phase, and we still don’t know how these drugs biologically affect the developing brain,” he said. “There’s an obligation for parents, doctors and teachers to respect the authenticity issue, and I’m not sure that’s always happening.”

Dr. Anderson said that every child he treats with A.D.H.D. medication has met qualifications. But he also railed against those criteria, saying they were codified only to “make something completely subjective look objective.” He added that teacher reports almost invariably come back as citing the behaviors that would warrant a diagnosis, a decision he called more economic than medical.

“The school said if they had other ideas they would,” Dr. Anderson said. “But the other ideas cost money and resources compared to meds.”

Dr. Anderson cited William G. Hasty Elementary School here in Canton as one school he deals with often. Izell McGruder, the school’s principal, did not respond to several messages seeking comment.

Several educators contacted for this article considered the subject of A.D.H.D. so controversial — the diagnosis was misused at times, they said, but for many children it is a serious learning disability — that they declined to comment. The superintendent of one major school district in California, who spoke on the condition of anonymity, noted that diagnosis rates of A.D.H.D. have risen as sharply as school funding has declined.

“It’s scary to think that this is what we’ve come to; how not funding public education to meet the needs of all kids has led to this,” said the superintendent, referring to the use of stimulants in children without classic A.D.H.D. “I don’t know, but it could be happening right here. Maybe not as knowingly, but it could be a consequence of a doctor who sees a kid failing in overcrowded classes with 42 other kids and the frustrated parents asking what they can do. The doctor says, ‘Maybe it’s A.D.H.D., let’s give this a try.’ ”

When told that the Rocaforts insist that their two children on Adderall do not have A.D.H.D. and never did, Dr. Anderson said he was surprised. He consulted their charts and found the parent questionnaire. Every category, which assessed the severity of behaviors associated with A.D.H.D., received a five out of five except one, which was a four.

“This is my whole angst about the thing,” Dr. Anderson said. “We put a label on something that isn’t binary — you have it or you don’t. We won’t just say that there is a student who has problems in school, problems at home, and probably, according to the doctor with agreement of the parents, will try medical treatment.”

He added, “We might not know the long-term effects, but we do know the short-term costs of school failure, which are real. I am looking to the individual person and where they are right now. I am the doctor for the patient, not for society.”

Related:  Government Sponsored Mind Control In America: The Teen Screen Scam   - 

Dave Hodges | When you are deemed to be mentally ill for not embracing totalitarianism and they come for you, what will you do?

Wednesday, April 25, 2012

Is This Where All the Ritalin Went? - Why Are They Drugging Our Soldiers?

Is This Where All The Ritalin Went?

According to an op-ed entitled “Why Are We Drugging Our Soldiers?” in the New York Times by Richard A. Friedman, “the number of Ritalin and Adderall prescriptions written for active-duty service members increased by nearly 1,000 percent in five years.” Might this explain, in part at least, the shortages of Ritalin and Adderall that have plagued students nationwide?

Since the start of the wars in Iraq and Afghanistan, there has been a large and steady rise in the prevalence of post-traumatic stress disorder among our troops. One recent study of 289,000 Americans who served in those countries found that the rates of the disorder jumped to 22 percent in 2008 from just 0.2 percent in 2002.

Given the duration of these wars and the length and frequency of deployments, when compared with other wars, perhaps such high rates of PTSD are not so surprising. Prolonged exposure to a perilous and uncertain combat environment might make trauma common.
But there is another factor that might be playing a role in the increasing rates of the disorder, one that has escaped attention: the military’s use of stimulant medications, like Ritalin and Adderall, in our troops.

There has been a significant increase in the use of stimulant medication. Documents that I obtained in late 2010 through the Freedom of Information Act, and have recently analyzed, show that annual spending on stimulants jumped to $39 million in 2010 from $7.5 million in 2001 — more than a fivefold increase. Additional data provided by Tricare Management Activity, the arm of the Department of Defense that manages health care services for the military, reveals that the number of Ritalin and Adderall prescriptions written for active-duty service members increased by nearly 1,000 percent in five years, to 32,000 from 3,000.

Stimulants are widely used in the civilian population to treat attention deficit hyperactivity disorder because they increase focus and attention. Short of an unlikely epidemic of that disorder among our soldiers, the military almost certainly uses the stimulants to help fatigued and sleep-deprived troops stay alert and awake. (A spokesman for Tricare attributed the sharp rise to “the increased recognition and diagnosis of A.D.H.D. by medical providers.” However, while there is greater recognition of the disorder, the diagnoses are concentrated in children and adolescents.)…

[continues in the New York Times]

 

Why Are We Drugging Our Soldiers?

Jon Han -  By RICHARD A. FRIEDMAN - Published: April 21, 2012  at the LA Times – h/t to MJ

SINCE the start of the wars in Iraq and Afghanistan, there has been a large and steady rise in the prevalence of post-traumatic stress disorder among our troops. One recent study of 289,000 Americans who served in those countries found that the rates of the disorder jumped to 22 percent in 2008 from just 0.2 percent in 2002.

Given the duration of these wars and the length and frequency of deployments, when compared with other wars, perhaps such high rates of PTSD are not so surprising. Prolonged exposure to a perilous and uncertain combat environment might make trauma common.

But there is another factor that might be playing a role in the increasing rates of the disorder, one that has escaped attention: the military’s use of stimulant medications, like Ritalin and Adderall, in our troops.

There has been a significant increase in the use of stimulant medication. Documents that I obtained in late 2010 through the Freedom of Information Act, and have recently analyzed, show that annual spending on stimulants jumped to $39 million in 2010 from $7.5 million in 2001 — more than a fivefold increase. Additional data provided by Tricare Management Activity, the arm of the Department of Defense that manages health care services for the military, reveals that the number of Ritalin and Adderall prescriptions written for active-duty service members increased by nearly 1,000 percent in five years, to 32,000 from 3,000.

Stimulants are widely used in the civilian population to treat attention deficit hyperactivity disorder because they increase focus and attention. Short of an unlikely epidemic of that disorder among our soldiers, the military almost certainly uses the stimulants to help fatigued and sleep-deprived troops stay alert and awake. (A spokesman for Tricare attributed the sharp rise to “the increased recognition and diagnosis of A.D.H.D. by medical providers.” However, while there is greater recognition of the disorder, the diagnoses are concentrated in children and adolescents.)

Stimulants do much more than keep troops awake. They can also strengthen learning. By causing the direct release of norepinephrine — a close chemical relative of adrenaline — in the brain, stimulants facilitate memory formation. Not surprisingly, emotionally arousing experiences — both positive and negative — also cause a surge of norepinephrine, which helps to create vivid, long-lasting memories. That’s why we tend to remember events that stir our feelings and learn best when we are a little anxious.

Since PTSD is basically a pathological form of learning known as fear conditioning, stimulants could plausibly increase the risk of getting the disorder.

The role of norepinephrine in the enhancement of memory was demonstrated in an elegant experiment led by Larry Cahill at the University of California, Irvine. He randomly gave a group of subjects either propranolol, a drug that blocks the effect of norepinephrine, or a placebo just before they heard one of two stories: an emotionally arousing one or a neutral one. He then tested their memory of the stories a week later and found that propranolol selectively impaired recall of the emotionally arousing story but not the neutral story. The clear implication of this study is that emotion raises norepinephrine, which then enhances memory. Block norepinephrine and you can impair emotional memory. With PTSD, a shocking combat situation elicits a hard-wired fear response — the flight-or-fight reaction — with intense emotional arousal and a surge of norepinephrine in the brain. This burns in the memory of the traumatic experience. It also promotes fear conditioning, a form of learning in which previously neutral stimuli in the environment — sights, sounds and smells, for example — become linked with a trauma. So, for a soldier injured in a bomb blast, anything like the sound of an explosion or the odor of burning is now a potent conditioned stimulus that can evoke the trauma and trigger symptoms of PTSD, like a flashback or startle reaction.

Because norepinephrine enhances emotional memory, a soldier taking a stimulant medication, which releases norepinephrine in the brain, could be at higher risk of becoming fear-conditioned and getting PTSD in the setting of trauma.

This possibility is supported by both animal and human studies. In rats, tiny injections of norepinephrine into the amygdala, a region of the brain that encodes fear, can enhance fear conditioning. And Marieke Soeter at the University of Amsterdam recently conducted an experiment in which college students were shown a picture paired with a small electric shock. Before viewing the pictures, subjects were randomly given yohimbine, a drug that releases norepinephrine in the brain, or a placebo. When students were tested 48 hours later, those who had received yohimbine had greater fear-associated learning and had a harder time “unlearning” the fear — when presented with the picture in the absence of a shock — than those students who had taken the placebo.

The study implies that soldiers exposed to elevated norepinephrine levels from taking stimulants are also at risk of relapse when re-exposed to the initial stressor. And because the treatment of PTSD involves unlearning fear responses, soldiers exposed to stimulants during trauma could well be more resistant to treatment.

And in fact, blocking the effects of norepinephrine with beta blockers can stop fear-conditioning and possibly even prevent post-traumatic stress disorder.

Roger Pittman, a psychiatrist at Harvard Medical School, led a small study in 2002 in which he randomly assigned emergency-room patients to either the beta blocker propranolol or a placebo within six hours of their experiencing a traumatic event. After one month, subjects who took the propranolol had significantly fewer symptoms of PTSD than subjects who took the placebo.

Does all of this prove that stimulants promote the development of post-traumatic stress disorder?

No. Because two things are correlated doesn’t mean there is a causal link. There are other factors that might play an important role, like incurring a traumatic brain injury, which is a known risk factor for the disorder, and growing steadily during these wars.

Still, it is an open question whether the use of stimulants in combat does more good than harm. The next step should be a rigorous epidemiologic study of a possible link between stimulants and PTSD in our troops.

Richard A. Friedman is a professor of psychiatry and director of the psychopharmacology clinic at Weill Cornell Medical College.

Related in Opinion

Friday, September 4, 2009

Do NOT use the new ADHD drug – INTUNIV!

Do NOT use the new ADHD drug!

Intuniv – a new and different once-daily ADHD drug – just got approved by the FDA for use in children as young as 6. BIG mistake! This is drug is being marketed as the 'kinder, gentler' ADHD drug because it's not a controlled substance and it's not addictive. But what it is... is very dangerous for your child.
Here are nine very good reasons you should NOT give your child this drug:

  1. It's only been tested for effectiveness in two short trials: one 8-week and one 9-week. No one knows if it will work after that. But everyone knows that ADHD is not an 8-week issue.
  2. The two long-term safety trials lasted an average of 10 months.
  3. Common adverse events, happening even at the lowest possible dose, include abdominal pain, sedation, dizziness, dry mouth, constipation, hypotension (very low blood pressure), loss of appetite, sedation, and somnolence (extreme sleepiness)
  4. Children taking Intuniv are also at risk for bradycardia (dangerously slow heart rate) and syncope (fainting)
  5. 12% of subjects (on Intuniv) dropped out of the trials because of adverse events, three times as many as in the placebo group
  6. In the short-term studies, a full 38% of patients suffered from excessive daytime sleepiness
  7. In the long-term studies, 45% of the patients suffered from extreme sleepiness, 26% reported headaches, and 15% complained of fatigue
  8. Some patients also reported psychiatric disorders, like anxiety, agitation, depression, and nightmares
  9. Less common adverse reactions reported by patients included sinus arrhythmia (irregular heartbeat), atrioventricular block (a disruption in the impulse that regulates the heart), chest pain, increased urinary frequency, asthma, and elevated liver enzymes
Bottom line: Intuniv (and other pharmaceutical "solutions" for ADHD) can cause a great deal more harm than good for your child. But there are several safe, natural protocols that really can help... and you can learn more about them on the HSI website.
-- Michele